5S-羟基-6R-（S-谷胱甘肽）-7E，9E，11Z，14Z-d5-二十碳四烯酸，甲酯； LTC4-d5甲酯；白三烯C4-d5甲酯

背景资料

Leukotriene C4-d5 （LTC4-d5） methyl ester contains five deuterium atoms at the 19， 19’， 20， 20 and 20 positions. It is intended for use as an internal standard for the quantification of LTC4 methyl ester by GC- or LC-mass spectrometry. LTC4 is the parent cysteinyl-leukotriene produced by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils， macrophages， and mast cells， and by transcellular metabolism in platelets. It is one of the constituents of slow-reacting substance of anaphylaxis and exhibits potent smooth muscle contracting activity. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute allergic hypersensitivity. The concentration of LTC4 required to produce marked contractions of lung parenchymal strips and isolated tracheal rings is about 1 nM. LTC4 methyl ester is a more lipid soluble form of LTC4. The biological activity of LTC4 methyl ester has not been reported.

保存条件

建议您在收到Cayman Chemical品牌的Leukotriene C4-d5 methyl ester （25 ug）产品后置于-80度保存，产品有效期为365天.

品牌介绍

Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

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