N-（2-羟乙基）-11-oxo-9α，15S-二羟基-prosta-5Z，13E-dien-1-amide-d4； PGD2-EA-d4 | Prostamide D2-d4；前列腺素D2乙醇酰胺-d4

背景资料

Prostaglandin D2 ethanolamide （PGD2-EA）-d4 contains four deuterium atoms. It is intended for use as an internal standard for the quantification of PGD2-EA by GC- or LC-mass spectrometry. PGD2-EA is a bioactive lipid produced by the sequential metabolism of anandamide （arachidonoyl ethanolamide） by cyclooxygenase （COX） enzymes， in particular by COX-2， and PGD synthase. The biosynthesis of PGD2-EA from anandamide can also be increased when anandamide metabolism is diminished by deletion of fatty acid amide hydrolase. PGD2-EA is inactive against recombinant prostanoid receptors， including the D prostanoid receptor. It increases the frequency of miniature inhibitory postsynaptic currents in primary cultured hippocampal neurons， an effect which is the opposite of that induced by anandamide.. PGD2-EA also induces apoptosis in colorectal carcinoma cell lines.

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建议您在收到Cayman Chemical品牌的Prostaglandin D2 Ethanolamide-d4 （50 ug）产品后置于-20度保存，产品有效期为365天.

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Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

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