产品详情
Thalidomide-5-(PEG8-Azide)
Thalidomide-5-(PEG8-Azide)
Thalidomide-5-(PEG8-Azide) is a PROTAC linker featuring a thalidomide ligand connected to a PEG spacer and an azide group. Azides are click chemistry handles that are capable of reacting with terminal alkynes or strained cyclooctynes. Thalidomide is a ligand for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction.
背景资料
Thalidomide-5-(PEG8-Azide)产品的分子式为C32H46N6O13,分子量为722.75582,纯度为98%,溶解度为DMSO, DCM, DMF, Acetonitrile
保存条件
Thalidomide-5-(PEG8-Azide)具体产品保存方法查看产品说明。
品牌介绍
BroadPharm是一个领先的以客户为中心的生物技术公司,总部位于圣地亚哥,BroadPharm致力于为全球客户提供高质量的PEG接头、Click Chemistry试剂、ADC接头、 PROTAC接头、药物递送脂质、核苷、亚磷酰胺和标记试剂。BroadPharm成立于2009年,生产超过2000种分散的,高纯度的聚乙二醇(PEG)试剂,目前这些PEG试剂广泛应用于生物偶联、抗体-药物偶联(ADC)治疗、药物递送和诊断领域。
FAQ
文献