产品详情
NA 209A | TR 1; (5R,10S,10aR)-1,10,10a,14,14aS,15bS-六氢-10,10a-二羟基-7-甲氧基-2,2-二甲基-5-(2-甲基-1-丙烯-1 -yl)-5H,12H-3,4-dioxa-5a,11a,15a-三氮杂环辛[lm]茚并[5,6-b]芴-11,15(2H,13H)-二酮 CAS:1219386-75-0
NA 209A|TR 1; (5R,10S,10aR)-1,10,10a,14,14aS,15bS-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propen-1-yl)-5H,12H-3,4-dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione
A tremorgenic mycotoxin that selectively inhibits the activation of Maxi-K potassium channels by charybdotoxin with a K1/2 value of 170 nM
背景资料
Verruculogen is a tremorgenic mycotoxin isolated from species of Penicillium, Aspergillus, and other fungi.{25045,25044} It selectively inhibits the activation of Maxi-K potassium channels by charybdotoxin with a K1/2 value of 170 nM.{20613} Verruculogen also promotes the release of excitatory neurotransmitters when injected directly into the brain of rats and, at high doses, arrests mouse mammary carcinoma cells in M phase of the cell cycle (MIC = 12.2 μM).{25047,25046}
保存条件
建议您在收到Cayman Chemical品牌的Verruculogen (1 mg)产品后置于-20度保存,产品有效期为730天.
品牌介绍
Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒,其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒,如:类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等;也提供多种高质量试剂,包括:类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.
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