产品详情
2-Probe bone affinity sampler(AF647-RIS (24 nmol) + 56-FAM-RISPC (24 nmol))
2-Probe bone affinity sampler(AF647-RIS (24 nmol) + 56-FAM-RISPC (24 nmol))
2-Probe bone affinity sampler(AF647-RIS (24 nmol) + 56-FAM-RISPC (24 nmol)),This sampler kit includes two imaging probes with different spectroscopic properties as well as variable bone affinities (AF647-RIS has stronger affinity than 5(6)-FAM-RISPC). The probes are fluorescent conjugates of risedronate, a widely used bisphosphonate drug in clinical applications, and its phosphonocarboxylate analogue. There is also an option of adding the calcein (a fluorescent molecule with even lower bone affinity) in the kit. The kit can be used for simultaneous detection with co-dosing and studies on effects of bone affinity, and is a great, economical complement to the 3-probe bone affinity kit. Spectroscopic properties of AF647-RIS: Maximum absorption wavelength (λmax (abs)): 648 nm Maximum emission wavelength (λmax (em)): 666 nm Extinction coefficient (M-1cm-1): 240,000 (0.1 M phosphate buffer, pH 7.0) Spectroscopic properties of 5(6)-FAM-RISPC: Maximum absorption wavelength (λmax (abs)): 493 nm Maximum emission wavelength (λmax (em)): 518 nm Extinction coefficient (M-1cm-1): 73,000 (0.1 M phosphate buffer, pH 7.2)
背景资料
2-Probe bone affinity sampler(AF647-RIS (24 nmol) + 56-FAM-RISPC (24 nmol)),2-Probe bone affinity sampler(AF647-RIS (24 nmol) + 56-FAM-RISPC (24 nmol))
保存条件
stored at ≤ -20 ºC and protected from light
品牌介绍
BioVinc是一家位于洛杉矶的私营生物技术公司。BioVinc提供骨靶向性荧光标记的双膦酸盐(Bisphosphonates)探针,以荧光成像技术推进骨骼研究,利用他们先进的双膦酸盐平台技术,可开发骨骼选择性治疗和诊断产品,以满足一些潜在的诊断及医疗需求。
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