2- [2-（3-氯-4-甲氧基苯基）乙基] -5-（3,5-二甲基-4-异恶唑基）-1-[（2S）-2-（4-吗啉基）丙基] -1H-苯并咪唑 CAS:136587-07-0

背景资料

cAMP-responsive element-binding protein binding protein (CREBBP) and E1A-associated protein p300 (EP300) are transcriptional co-activators. Each contains a bromodomain, which recognizes acetylated lysine residues on target proteins. SGC-CBP30 is a potent inhibitor of CREBBP and EP300 bromodomains (IC50s = 21-69 and 38 nM, respectively).{26201} Developed by the Structural Genomics Consortium ((www.thesgc.org/chemical-probes/SGC-CBP30)), this compound displays over 40-fold selectivity for CREBBP over BRD4(1) and is functional in cells.

保存条件

建议您在收到Cayman Chemical品牌的SGC-CBP30 (50 mg)产品后置于-20度保存，产品有效期为730天.

品牌介绍

Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

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