产品详情
环氧美沙酮| Inspra; （7α，11α，17α）-9,11-环氧-17-羟基-3-氧代-孕烯-4-烯-7,21-二羧酸，γ-内酯，7-甲酯 CAS:146464-95-1
Epoxymexrenone|Inspra; (7α,11α,17α)-9,11-epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic acid, γ-lactone, 7-methyl ester
A potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor (IC50 = 122 nM); indicated for the treatment of hypertension and heart failure
背景资料
Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor (IC50 = 122 nM), demonstrating little activity towards other steroid receptors (IC50 > 9 µM for glucocorticoid, androgen, progesterone, and estrogen receptors).{18724} Aldosterone antagonists such as this compound have been indicated for the treatment of hypertension and heart failure.{25616}
保存条件
建议您在收到Cayman Chemical品牌的Eplerenone (5 mg)产品后置于-20度保存，产品有效期为730天.
品牌介绍
Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.
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