产品详情
1-β-D-阿拉伯呋喃糖基胞嘧啶| NSC 287459 | NSC 63878 | U-19920A; 4-氨基-1-β-D-阿拉伯呋喃糖基-2(1H)-嘧啶酮 CAS:149759-96-6
1-β-D-Arabinofuranosylcytosine|NSC 287459|NSC 63878|U-19920A; 4-amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone
A nucleoside analog that differs from cytosine by the presence of a hydroxyl group at the 2’ position of the sugar residue; triphosphorylated in vivo to produce ara-CTP, a competitive inhibitor of DNA polymerases α and β (Kis = 4 and 32 µM, respectively)
背景资料
Cytarabine is a nucleoside analog that differs from cytosine by the presence of a hydroxyl group at the 2’ position of the sugar residue. It is triphosphorylated in vivo to produce ara-CTP, a competitive inhibitor of DNA polymerases α and β (Kis = 4 and 32 µM, respectively).{26180,26181,26183} At low concentrations, ara-CTP is incorporated into DNA, slowing but not stopping DNA synthesis.{26184} Cytarabine is effective in the treatment of leukemias.{26184} It can also have antiviral actions on certain types of viruses.{26182}
保存条件
建议您在收到Cayman Chemical品牌的Cytarabine (1 g)产品后置于-20度保存,产品有效期为730天.
品牌介绍
Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒,其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒,如:类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等;也提供多种高质量试剂,包括:类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.
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