产品详情
背景资料
CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.
应用类型
IHC-P, ICC, FC (QC tested)
免疫原
Human thymocytes and T lymphocytes.
宿主
Mouse IgG2a
反应性
The antibody MEM-115 recognizes an extracellular epitope in the D1 domain of CD4 antigen, a 55 kDa transmebrane glycoprotein expressed on a subset of T lymphocytes (“helper“ T cells) and also on monocytes, tissue macrophages and granul
保存条件
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
品牌介绍
EXBIO是捷克一家著名的生物试剂公司,专注于流式细胞术配套试剂的开发。自1990年成立以来,EXBIO公司研发和制造的抗体分销全球。目前,EXBIO可提供超过4000种质优、价廉的研究和临床应用抗体,涵盖了血液学,免疫学,癌症,干细胞和细胞生物学等领域,如:CD分子、细胞粘附分子、细胞骨架、凋亡、细胞信号传导、肿瘤标志物、人血型、HLA、生殖等研究用抗体,涉及荧光染料如FITC、PE、PE-Cy5、PE-Cy7、APC、PerCP、PerCP-Cy5.5、Pacific Blue、Pacific Orange、Alexa Fluor 488、Alexa Fluor 647、Alexa Fluor 700、Biotin等多达13种,满足客户各类实验需求。
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