DBF | NSC 645658；2- [3-氧代-6-（苯基甲氧基）-3H-噻吨-9-基]-苯甲酸苯基甲基酯 CAS:1624-62-0

背景资料

Dibenzylfluorescein is a fluorogenic probe that acts as a substrate for specific cytochrome P450 (CYP) isoforms, including CYP3A4, CYP2C8, CYP2C9, CYP2C19, and aromatase (CYP19).{27561,27560,27562} ​Dibenzylfluorescein​ is dealkylated by these CYP isoforms to produce fluorescein benzyl ether, which is further hydrolyzed to fluorescein by the addition of base (typically 2 M NaOH).{27562} ​Dibenzylfluorescein​ is typically used near its apparent Km value of 0.87-1.9 µM.{27561,27560,27562} The fluorescence of fluorescein is evaluated using excitation/emission wavelengths of 485/538 nm. ​Dibenzylfluorescein​ is used to detect changes in CYP catalytic activity caused by drugs or disease.{27561,27563}

保存条件

建议您在收到Cayman Chemical品牌的​Dibenzylfluorescein​ (10 mg)产品后置于-20度保存，产品有效期为730天.

品牌介绍

Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

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