产品详情
达比加群酯 CAS:16742-51-1
Dabigatran etexilate
A double prodrug that undergoes in vivo hydrolytic cleavage to produce dabigatran, a potent thrombin inhibitor (Ki = 4.5 nM); shows antithrombotic efficacy in animal models of thrombosis, with a rapid onset of action
背景资料
Dabigatran etexilate is a double prodrug that undergoes in vivo hydrolytic cleavage to produce dabigatran (Item No. 17133), a potent thrombin inhibitor (Ki = 4.5 nM).{28063,28064} Dabigatran also inhibits trypsin (Ki = 50.3 nM), but only weakly inhibits other serine proteases.{28063,28064} The prodrug dabigatran etexilate shows antithrombotic efficacy in animal models of thrombosis, with a rapid onset of action.{28064} It is not metabolized by cytochrome P450 isozymes and has a low potential for drug-drug interactions.{28064}
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Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒,其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒,如:类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等;也提供多种高质量试剂,包括:类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.
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