THDOC |四氢脱氧皮质酮

背景资料

TetraHydroDesOxyCorticosterone (THDOC) is a stress related neuroactive steroid. THDOC is a metabolite of desoxycoritcosterone (DOC) and progesterone and DOC is a steroid in the synthesis pathway to aldosterone. THDOC is produced by the adrenal in parallel with cortisol at stress and is regulated by ACTH. THDOC is a potent positive modulator of the GABA A receptor. THDOC passes the blood-brain barrier and can be found in the brain after stress in nanomolar concentrations.

应用类型

Radioimmunoassay (RIA)

免疫原

BSA-coupled THDOC

宿主

鸡

反应性

THDOC

保存条件

Store at 4°C or at -20°C for long-term storage; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

品牌介绍

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