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IL2 |白介素2

IL2 | Interleukin-2

人白细胞介素-2(IL 2)是一种分泌的细胞因子,其对于T和B淋巴细胞的增殖是重要的。该细胞因子的受体是异源三聚体蛋白复合物,其γ链也由白细胞介素-4(IL 4)和白细胞介素-7(IL 7)共享。该基因在成熟胸腺细胞中的表达是单等位基因的,这代表了用于控制单个基因的精确表达的不寻常的调节模式。小鼠中类似基因的靶向破坏导致溃疡性结肠炎样疾病,这表明该基因在对抗原刺激的免疫应答中起重要作用。在一些研究中已显示IL 2具有抗肿瘤作用。

货号:IMS01-127-320品牌:Agrisera 规格:100ul价格:询价元 说明书:点击查看 COA下载:点击查看

背景资料


Human interleukin-2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin-4 (IL4) and interleukin-7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies.


应用类型


Total, purified IgY


免疫原


purified full length recombinant protein UniProt: P60568


宿主



反应性


保存条件


Store at 4°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

品牌介绍


Agrisera公司提供1000种用于植物和藻类细胞生物学研究的一抗,2000多种二抗。Agrisera公司提供的植物领域的抗体涵盖拟南芥、莱茵衣藻、蓝藻、松柏类、硅藻、大豆、大麦、蒺藜苜蓿、烟草、稻、菜豆、小立碗藓、杨树、豌豆、番茄、马铃薯、菠菜、小麦、玉米、葡萄等多个物种,此外还有水生生物类(藻类、鱼)抗体,细菌、昆虫、真菌抗体。针对植物蛋白质的保守氨基酸序列,Agirsera还独家开发了数十种通用抗体(global antibodies),这类抗体几乎可以与所有的高等植物及藻类产生免疫反应,可为研究人员提供极为方便的选择。

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