产品详情
ASY1 |突触表型蛋白1(单克隆)
ASY1 | Asynaptic phenotype protein 1 (monoclonal)
同源染色体的配对和联会是正常染色体分离和减数分裂期间通过重组交换遗传物质所必需的。联会在粗线期完成,随后形成称为联会复合体(SC)的三分蛋白质结构。在酵母中,HOP 1对于SC的形成是必需的,并且在前期I期间沿着染色体轴定位。拟南芥(AtASY 1)、芸苔属(BoASY 1)和水稻(OsPAIR 2)中的同源物已经通过分析由于同源染色体的突触严重减少而显示生育力降低的突变体而分离。对这些基因的分析表明,它们通过定位于SC的轴向/侧向元件,在SC的配对和形成中发挥与HOP 1类似的作用。
背景资料
Pairing and synapsis of homologous chromosomes is required for normal chromosome segregation and the exchange of genetic material via recombination during meiosis. Synapsis is complete at pachytene following the formation of a tri-partite proteinaceous structure known as the synaptonemal complex (SC). In yeast, HOP1 is essential for formation of the SC, and localises along chromosome axes during prophase I. Homologues in Arabidopsis (AtASY1), Brassica (BoASY1) and rice (OsPAIR2) have been isolated through analysis of mutants that display decreased fertility due to severely reduced synapsis of homologous chromosomes. Analysis of these genes has indicated that they play a similar role to HOP1 in pairing and formation of the SC through localisation to axial/lateral elements of the SC.
应用类型
ELISA (ELISA), Western blot (WB)
免疫原
KLH-conjugated synthetic pepitde chosen from Triticum aestivum ASY1 UniProt: A7TVU8
宿主
小鼠
反应性
Triticum aestivum
保存条件
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
品牌介绍
Agrisera公司提供1000种用于植物和藻类细胞生物学研究的一抗,2000多种二抗。Agrisera公司提供的植物领域的抗体涵盖拟南芥、莱茵衣藻、蓝藻、松柏类、硅藻、大豆、大麦、蒺藜苜蓿、烟草、稻、菜豆、小立碗藓、杨树、豌豆、番茄、马铃薯、菠菜、小麦、玉米、葡萄等多个物种,此外还有水生生物类(藻类、鱼)抗体,细菌、昆虫、真菌抗体。针对植物蛋白质的保守氨基酸序列,Agirsera还独家开发了数十种通用抗体(global antibodies),这类抗体几乎可以与所有的高等植物及藻类产生免疫反应,可为研究人员提供极为方便的选择。
FAQ
文献