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KLH |匙孔血蓝蛋白

KLH | Keyhole limpet hemocyanin

钥孔血蓝蛋白(KLH)是一种大的含铜蛋白,由分子量为400 kDa的亚基组成。它存在于海洋软体动物Megathura crenulata的血淋巴中。这种细胞外呼吸蛋白具有许多免疫刺激特性,包括通过与T细胞、单核细胞、巨噬细胞和多形核淋巴细胞相互作用来增强宿主免疫应答的能力。自发现以来,KLH主要用作疫苗和抗原的载体,并在抗菌治疗等方案中用作辅助治疗。

货号:AS99-001品牌:Agrisera 规格:50ug价格:询价元 说明书:点击查看 COA下载:点击查看

背景资料


Keyhole limpet hemocyanin (KLH) is a large cooper-containing protein consisting of subunits with MW of 400 kDa. It is found in the hemolymph of the sea mollusk Megathura crenulata. This extracellular respiratory protein  has many immunostimulatory properties, including the ability to enhance the host's immune response by interacting with T cells,  monocytes, macrophages, and polymorphonuclear lymphocytes. Since its discovery, KLH has been used primarily as a carrier for vaccines and antigens and as adjuvant treatment in regimens such as antimicrobial therapy.


应用类型


ELISA (ELISA), Immunolocalization (IL), Western blot (WB)


免疫原


Purified keyhole limpet hemocyanin (KLH), whole molecule,


宿主



反应性


Megathura crenulata - most commonly used carrier protein

保存条件


Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

品牌介绍


Agrisera公司提供1000种用于植物和藻类细胞生物学研究的一抗,2000多种二抗。Agrisera公司提供的植物领域的抗体涵盖拟南芥、莱茵衣藻、蓝藻、松柏类、硅藻、大豆、大麦、蒺藜苜蓿、烟草、稻、菜豆、小立碗藓、杨树、豌豆、番茄、马铃薯、菠菜、小麦、玉米、葡萄等多个物种,此外还有水生生物类(藻类、鱼)抗体,细菌、昆虫、真菌抗体。针对植物蛋白质的保守氨基酸序列,Agirsera还独家开发了数十种通用抗体(global antibodies),这类抗体几乎可以与所有的高等植物及藻类产生免疫反应,可为研究人员提供极为方便的选择。

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