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N-(甲基磺酰基)-2-(2-丙炔氧基)-苯己酰胺; MS-PPOH

N-(methylsulfonyl)-2-(2-propynyloxy)-benzenehexanamide; MS-PPOH

Arachidonic acid is converted by microsomal CYP450 enzymes to a variety of epoxides, .omega.-1 and .omega.-hydroxylated compounds via what is known as the epoxidase pathway.{313,403,823} MS-PPOH is a selective inhibitor of the epoxygenation reactions catalyzed by specific CYP450 isozymes.{8589} MS-PPOH inhibits the formation of arachidonate 11,12-epoxides by CYP4A2 and CYP4A3 enzymes with an IC50 value of 13 uM, but has no effect on the formation of 20-HETE, the .omega.-hydroxylation product of CYP4A1.{8588}

货号:75770-1品牌:Cayman Chemical 规格:1mg价格:询价元 说明书:点击查看 COA下载:点击查看

背景资料


Arachidonic acid is converted by microsomal CYP450 enzymes to a variety of epoxides, .omega.-1 and .omega.-hydroxylated compounds via what is known as the epoxidase pathway. MS-PPOH is a selective inhibitor of the epoxygenation reactions catalyzed by specific CYP450 isozymes. MS-PPOH inhibits the formation of arachidonate 11,12-epoxides by CYP4A2 and CYP4A3 enzymes with an IC50 value of 13 uM, but has no effect on the formation of 20-HETE, the .omega.-hydroxylation product of CYP4A1.

保存条件


建议您在收到Cayman Chemical品牌的MS-PPOH (1 mg)产品后置于-20度保存,产品有效期为730天.

品牌介绍


Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒,其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒,如:类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等;也提供多种高质量试剂,包括:类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

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